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The Gao Laboratory @ BCM Neuroscience
Decoding protein interactions in the brain
Research Areas
Like communities, individual proteins carry out complex biological functions by engaging each other in interactions and networks. Conversely, the dysregulation of these interactions often contributes to phenotypes seen in neurodevelopmental and neuropsychiatric conditions.
We utilize multi-omic target identification and high-throughput phenotyping strategies to uncover new mechanisms of protein interaction in diverse models of brain conditions. We further seek to develop innovative approaches to alleviate phenotypes through modulating experimentally evidenced functional interactions.
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